Professor Titilayo Fakeye is a Professor of Clinical Pharmacy and Pharmacy Practice. She has done a lot of work on herb-drug interaction, safety issues of the combinations, and some studies on effect of pharmacists' intervention on patients with specific non-communicable diseases. She is currently interested in implementation of some of the results obtained from studies in pharmacy practice using targeted intervention strategies especially. She has been a recipient of the DBT/TWAS and CAS/TWAS fellowship grants. A keen interest in Pharmacy Practice has made her spend some time at The State University of New York, United States of America (2011) and a recipient of the Pharmabridge where she visited the Skagg's School of Pharmacy and Pharmaceutical Sciences (2017) understudying the teaching methods for Pharmacy students especially. Prof Fakeye has a passion for quality assurance in Higher Education Learning and has been chosen among others in Anglophone West Africa for the Training in Internal Quality Assurance in West Africa (TRAINIQAfrica) March, 2015 – June, 2016. Organised by the University of Duisburg-Essen in collaboration with German Academic Exchange Service (DAAD), Higher Education Management (DIES) and HRK (Germany) and United Nations Educational, Scientific and Cultural Organization (UNESCO) in Ghana, Germany and Nigeria.
Prof Fakeye has published extensively in evaluating local plants for their biological activities including Hibiscus sabdariffa in which the antimicrobial, anxiolytic/sedative and immunomodulatory activities and the toxicity profile were established. Other studies established the anti-inflammatory and antimicrobial properties of the basic fraction of the methanol extract of Picralima nitida with the cream formulation of the basic fraction found effective for human dermatomycosis. Her findings underscored the need for healthcare providers to take cognisance of likelihood of herb use when taking patient’s medication history thus necessitating proper counseling of patients based on series of studies carried out on drug use among different populations, attitude of patients to use of herbal agents, and tendency to co-administer western drugs and herbal medicines showing gross deficiency and irrational assumptions on the use of herbs and drugs regardless of educational background as well as institutionalized or ambulatory status. The adverse reactions to use of drugs/herbs among selected populations including pregnant women and university community members were also established. Knowledge base of pharmacists and physicians regarding herbal agents sold in Nigeria were found deficient suggesting the need for additional training in pharmacology of herbs in order to ensure adequate counselling. A few studies evaluated the mechanism of interactions between some of the herbs and drugs gave an indication of activities of cytochrome P450 isozymes. As a result of unearthing extensive herb use among diabetes patients, studies are ongoing to evaluate the effect of co-administration of herbs with oral hypoglycaemic agents, and the mechanism of interactions specifically interaction of extracts of Hibiscus sabdariffa, Vernonia amygdalina and Ocimum gratissimum and Moringa spp with prescription drugs for hypertension, diabetes and dyslipidemia human volunteers.
